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. 2012 Jul 13;3:135. doi: 10.3389/fphar.2012.00135

Table 6.

Effect of Gl-BSP on T lymphocyte subpopulation in S180-bearing mice (n = 3, x¯±s).

Group Dose (mg kg−1 × days) CD4+ (%) CD8+ (%) CD4+/CD8+
Normal 33.67 ± 0.94 18.14 ± 1.46 1.86 ± 0.11
Model 20.98 ± 0.26### 9.46 ± 0.48### 2.22 ± 0.12###
Gl-BSP 50 mg kg−1 × 14 22.73 ± 0.31** 11.27 ± 0.55** 2.02 ± 0.09*
100 mg kg−1 × 14 22.99 ± 0.92** 11.95 ± 0.64*** 1.93 ± 0.03**
200 mg kg−1 × 14 23.81 ± 1.08*** 12.14 ± 0.05*** 1.96 ± 0.10**

S180-bearing mice were administrated intragastrically with Gl-BPS (50, 100, or 200 mg kg−1) or physiological saline respectively for 14 days; single splenic lymphocytes were labeled with anti-mouse CD4-FITC and anti-mouse CD8-PE. The CD4 and CD8 T-cell subpopulations were analyzed by flow cytometry using a FACS Calibur. ###P < 0.001 model group vs. normal group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. model group.