Table 7.
Effect of Gl-BSP on Production of Serum Cytokines and NO in S180-bearing mice (n = 10, ).
| Group | IL-2 (pg ml−1) | IFN-γ (pg ml−1) | TNF-α (pg ml−1) | NO2− (μM) | |
|---|---|---|---|---|---|
| Normal control | – | UD | UD | UD | 6.78 ± 4.94 |
| S180-bearing control | – | UD | 11.73 ± 3.53 | UD | 4.82 ± 3.74 |
| Gl-BSP | 50 mg kg−1 | UD | 13.24 ± 3.48 | UD | 12.97 ± 2.45 |
| 100 mg kg−1 | UD | 20.13 ± 2.93** | 20.62 ± 16.8 | 17.32 ± 5.30** | |
| 200 mg kg−1 | 3.4 ± 2.46*** | 67.42 ± 5.47*** | 72.58 ± 33.40*** | 35.63 ± 10.0*** | |
S180-bearing mice were administrated intragastrically with Gl-BPS (50, 100, 200 mg kg−1) or physiological saline respectively for 14 days. At the end of experiment, the serum was collected and the production of serum cytokines was detected by ELISA. Serum NO level was measured by Griess reagent. **P < 0.01, ***P < 0.001 vs. S180-bearing control; UD: undetected.