Table 8.

Effect of Gl-BSP-treated serum of S180-bearing mice preincubated with cytokine-neutralizing antibodies on the proliferation of S180 and PG cells (n = 10, $\overline{x}\pm \text{s}$).

Group	Inhibitory ratio (%)
	S180	PG
Gl-BSP 200 mg kg−1-treated serum alone	55.6 ± 1.7	45.1 ± 2.4
Gl-BSP 200 mg kg−1-treated serum + anti-TNF-α	32.5 ± 1.2***	29.0 ± 4.0***
Gl-BSP 200 mg kg−1-treated serum + anti-IFN-γ	45.0 ± 2.4***	34.1 ± 3.0***
Gl-BSP 200 mg kg−1-treated serum + anti-TNF-α + anti-IFN-γ	11.3 ± 0.9***	15.8 ± 3.3***

Gl-BSP 200 mg kg⁻¹-treated serum of S180-bearing mice preincubated with or without various cytokine-neutralizing antibodies (anti-TNF-α, 150 ng ml⁻¹, and/or anti-IFN-γ, 150 ng ml⁻¹) at 37°C for 90 min before addition to S180 or PG cells cultures. Data are the mean ± SD of 3 separate experiments. ***P < 0.001 vs. Gl-BSP 200 mg kg⁻¹-treated serum.