Table S2.
Multivariate analysis of the joint phenotype of low estimated glomerular filtration rate and history of cataract surgery with plasma pentosidine levels as a binary variable
| Group 1c | Group 2c | Group 4c | |
|---|---|---|---|
| Low eGFR | No | Yes | Yes |
| History of cataract surgery | Yes | Yes | No |
| RR (95% CI) | RR (95% CI) | RR (95% CI) | |
|
|
|||
| Model 1 (without age in the model)a | |||
| Pentosidine | 0.89 (0.30–2.62) | 3.48 (1.24–9.76) | 1.59 (0.76–3.32) |
| Hypertension | 0.44 (0.13–1.49) | 3.39 (0.63–18.40) | 13.57 (1.64–111.93) |
| Diabetic retinopathy | 2.84 (0.77–10.52) | 6.45 (1.96–21.16) | 3.21 (1.15–8.97) |
| Model 2 (with age in the model)b | |||
| Pentosidine | 0.76 (0.25–2.33) | 2.81 (0.91–8.71) | 1.33 (0.61–2.89) |
| Age | 1.14 (1.06–1.24) | 1.21 (1.12–1.31) | 1.08 (1.03–1.14) |
| Hypertension | 0.26 (0.07–0.996) | 1.29 (0.21–8.06) | 9.97 (1.19–83.58) |
| Diabetic retinopathy | 3.80 (0.95–15.17) | 8.81 (2.33–33.35) | 3.60 (1.20–10.74) |
Notes:
a
Apart from pentosidine, only covariates (history of hypertension and diabetic retinopathy) which were statistically significant in the final model are shown;
b
apart from pentosidine, only covariates (history of hypertension and diabetic retinopathy) which were statistically significant in the final model are shown;
c
group 3 is the referent category.
Abbreviations: CI, confidence interval; eGFR, estimated glomerular filtration rate; RR, relative risk.