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Temporal correlation between membrane potential (MP) and cytosolic free calcium concentration ([Ca2+]c) oscillations (adapted from Ref. 11). Islets from wild mice were perifused with a solution containing 8 (C and D) or 10 mM glucose(A and B) as indicated. The MP was measured in a β-cell within an islet, and [Ca2+]c was measured simultaneously in the same islet.
