Fig. 9.

Simulated influence of veratridine on slow [Ca²⁺]_c oscillations in β-cells. Addition of veratridine was simulated by decrease of half-activated potential for Na⁺ channels in the model by Fridlyand et al. (51). (Half-activated potential for Na⁺ channels was decreased from −104 to −94 mV at arrow 1 and from −94 to −84 mV at arrow 2 in B). A: V_P. B: [Ca²⁺]_c. C: [Na⁺]_c. D: I_Na.