Table 1.
Baseline Characteristics of 207 patients
| All patients | No AKI | AKI | P-values | |
|---|---|---|---|---|
| Total number of patients | 207 | 147 (71) | 60 (29) | |
| Age (year) | 80 [74-85] | 80 [73-84] | 80 [76-86] | 0.19 |
| Female | 85 (41) | 59 (40) | 26 (43) | 0.53 |
| Medical History | ||||
| Arterial Hypertension | 152 (73) | 106 (72) | 46 (76) | 0.27 |
| Heart Failure | 103 (50) | 67 (46) | 36 (60) | 0.03 |
| Coronary artery disease | 100 (48) | 66 (45) | 34 (57) | 0.09 |
| Diabetes mellitus | 69 (33) | 49 (33) | 20 (33) | 0.87 |
| Chronic kidney disease | 92 (44) | 57 (39) | 35 (58) | < 0.01 |
| Neoplastic disease | 27 (13) | 20 (14) | 7 (12) | 0.27 |
| Long term medication use | ||||
| Diuretics | 153 (74) | 105 (71) | 48 (80) | 0.06 |
| Betablockers | 123 (59) | 83 (54) | 40 (66) | 0.11 |
| Nitrates | 44 (21) | 30 (20) | 14 (23) | 0.57 |
| Renin Angiotensin System-Blockers | 129 (62) | 88 (61) | 41 (68) | 0.34 |
| Aspirin | 85 (41) | 60 (41) | 25 (42) | 0.75 |
| Anticoagulation | 77 (37) | 50 (34) | 27 (45) | 0.11 |
| Vital status | ||||
| Blood pressure (mmHg) | ||||
| Systolic | 136 [115-152] | 138 [117-157] | 130 [112-144] | 0.05 |
| Diastolic | 84 [69-96] | 84 [74-97] | 75 [67-92] | 0.09 |
| Heart rate (per minute) | 85 [73-102] | 86 [74-100] | 85 [75-107] | 0.63 |
| Respiratory rate (per minute) | 20 [18-27] | 20 [16-28] | 22 [18-26] | 0.63 |
| Oxygen saturation (%) | 97 [95-98] | 96 [95-98] | 97 [93-98] | 0.91 |
| Body Mass Index (kg/m2) | 26 [23-30] | 26 [23-30] | 26 [24-30] | 0.58 |
| Noninvasive CVP (cmH20) | 13 [9-18] | 13 [8-20] | 13 [8-17] | 0.59 |
| Laboratory values | ||||
| LV ejection fraction (%) | 40 [25-55] | 45 [25-55] | 40 [29-50] | 0.87 |
| Leucocytes (x109/L) | 8.1 [6.5-10.6] | 8.1[6.7-10.0] | 8.2 [6.9-12.0] | 0.23 |
| Hemoglobin (g/l) | 123 [114-139] | 127 [120-139] | 122 [107-139] | 0.25 |
| C-reactive protein (mg/l) | 11.6 [4.2-32.3] | 9.4 [4.1-32.9] | 20.4 [8.1-40.3] | 0.03 |
| Urea (mmol/l) | 9.2 [7.1-13.2] | 8.9 [6.9-12.8] | 11.8 [8.5-18.1] | < 0.01 |
| Uric acid (mmol/l) | 461 [370-582] | 448 [347-576] | 505 [407-624] | 0.02 |
| Creatinine (mmol/l) | 100 [78-143] | 97 [76-132] | 140 [91-203] | < 0.01 |
| Baseline eGFR (ml/min)* | 52 [35-74] | 57 [38-75] | 42 [27-63] | < 0.01 |
| NGAL (ng/ml) | 79.6 [60.0-133.6] | 75.4 [60.0-113.9] | 114.5 [67.1-201.5] | < 0.01 |
| BNP (pg/ml) | 1377 [847-2428] | 1321 [792-2491] | 1470 [731-2444] | 0.49 |
| Troponin T (ug/l) | 0.02 [0.01-0.04] | 0.01 [0.01- 0.30] | 0.03 [0.01-0.60] | < 0.01 |
Data are presented as median [interquartile range], number of patients (%)as appropriate; Abbreviations:eGFR denotes estimated glomerular filtration rate, NGAL denotes Neutrophil gelatinase-associated lipocalin; BNP denotes B-type natriuretic peptide, CVP denotes central venous pressure