Table 1.
Baseline characteristics of patients and operations
| Parameter | Controls (n = 20) |
Esmolol (n = 20) |
Phenylephrine (n = 20) |
Kruskal- Wallis test |
|---|---|---|---|---|
| Age, years | 32 (27-38) | 32 (28-39) | 33 (27-41) | NS |
| Body weight, kg | 50 (48-55) | 53 (49-59) | 55 (48-60) | NS |
| Start of surgery, minutes | 70 (65-80) | 70 (70-80) | 80 (60-90) | NS |
| End of surgery, minutes | 130 (115-155) | 150 (130-180) | 150 (130-180) | NS |
| Operating time, minutes | 60 (40-80) | 75 (50-100) | 70 (50-100) | NS |
| Blood loss, mLa | 30 (30-55) | 35 (25-70) | 40 (30-70) | NS |
| MAP, mm Hg | ||||
| Baseline | 88 (81-94) | 92 (87-102) | 92 (88-98) | NS |
| Non-surgery | 77 (68-80) | 78 (73-85) | 83 (75-93) | NS |
| Surgery | 92 (87-96) | 90 (84-92) | 95 (85-94) | P < 0.03 |
| 5 to 180 minutes | 82 (59-86) | 82 (80-90) | 92 (85-94) | P < 0.02 |
Data are the median (25th to 75th percentile) for the group. aCollected by suction and on sponges, not including blood in removed tissue. MAP, mean arterial pressure; NS, not significant.