FIGURE 2.

Galectin recognition. (A) Schematic representation of galectin domain organization; (B) Schematic illustration of cis-interactions of proto, chimera, and tandem repeat galectins with host cell surface glycans. (C) Schematic illustration of trans-interactions of proto, chimera, and tandem repeat galectins with host cell surface and microbial glycans. Proto- and trandem repeat-type galectins can cross-link host and microbial glycans. Chimera galectins (galectin-3) can recognize microbial glycans but it is not clear that they can cross-link them to the host cell surface.