Table 7.
Comparison of clinical outcome with previous reports
| Author Journal | Gorovoy et al. Cornea, 2006 [5] | Koenig et al. Cornea, 2007 [6] | Koenig et al. Ophthalmology, 2007 [7] | Bahar et al. Ophthalmology, 2008 [8] | Kobayashi et al. Cornea, 2008 [9] | Kobayashi et al. Am J O, 2008 [10] | Price et al. Ophthalmology, 2010 [19] | Hirayama et al. |
|---|---|---|---|---|---|---|---|---|
| Operation | DSAEK | DSAEK | DSAEK | DSAEK | DSAEK | nDSAEK | DSAEK | DSAEK/ nDSAEK |
| Study design | Retrospective | Prospective | Prospective | Prospective | Prospective | Prospective | Prospective | Retrospective |
| Number of eyes (eyes) | 16 | 34 | 26 | 45 | 14 | 6 | 173 | 54 |
| Disease (eyes) | FED 9 | FED 11 | FED 12 | FED 28 | ALI-BK 14 | ALI-BK 6 | FED 147 | ALI-BK |
| PBK 7 | P/ABK 23 | P/ABK 14 | PBK 12 | P/ABK 23 | ||||
| ICE syndrome 2 | Other endothelial failure 3 | |||||||
| Failed graft 3 | ||||||||
| M:F | 7:9 | 6:28 | 6:20 | 20:25 | 1:13 | 2:4 | 69:104 | 5:49 |
| Mean age (years) | 66 | 73.8 | 75.9 | 70.2 | 74.2 | 74.5 | 72 | 76 |
| Follow-up time | 1 year | 6 months | 3 months | 9.8 months | 228 ±132 days | 6 months | 1 year | 6 month |
| Postoperative BSCVA | 20/40 or better (except three eyes with macular scar, optic dystrophy, primary graft failure) | Mean 20/42 (62% achieved 20/40 or better) | Mean 20/45 | Mean 20/44 | 20/40 or better (23% achieved 20/20) | More than 20/32 (33% achieved 20/20) | – | Mean 20/29 (13% achieved 20/20) |
| Postoperative SE (D) | – | 0.97 | 0.82 | 0.96 | – | – | – | −0.15 |
| Postoperative astigmatism (D) | – | 1.80 | 2.12 | 1.36 | 0.53 | 0.85 | – | 1.5 |
| Postoperative ECD (/mm2) | 1,714 (except one eye of primary graft failure) | 1,396 | – | 1,735 | 1,654 | 2,391 | 1,743 | 1,124 |
| Cell loss | 41% | 50% | – | 36% | 45% | 26% | 38% | 52% |
| Complications during operation (eyes) | – | – | – | – | Vitreous prolapse 2 (14%) | None | – | Posterior capsule rupture 3 (5.5%) |
| Postoperative complications (eyes) | – | |||||||
| Graft failure | 1 (6%) | 3 (9%) | – | 1 (2%) | – | 0 (0%) | – | – |
| Dislocaton | 4 (25%) | 9 (27%) | 9 (35%) | 7 (16%) | 2 (14%) | 1 (17%) | 10 (6%) | 6 (11%) |
| Acute rejection | – | 6 (18%) | 3 (12%) | 1 (2%) | – | – | 9 (5%) | 0 (0%) |
| Elevated IOP | – | – | – | 3 (7%) | – | – | 27 (16%) | 3 (6%) |
| Papillary block | – | 1 (3%) | 1 (4%) | – | – | 0 (0%) | 0 (0%) | 1 (2%) |
| Others | Interface opacity 2 (4%) | Subclinical endothelial rejection 1 (17%) | Retinal detachment 1(<1%) | CME 1 (2%) | ||||
| CME 1 (2%) | Anterior synechiae 2 (1%) |
DSAEK; Descemet’s stripping automated enthothelial keratoplasty, nDSAEK; non-Descemet’s stripping automated enthothelial keratoplasty, FED; Fuchs’ endothelial dystrophy, PBK; pseudophakic bullous keratopathy, ABK; aphakic bullous keratopathy, ALI-BK; bullous keratopathy secondary to argon laser iridotomy, ICE syndrome; iridocorneal endothelial syndrome, SE; spherical equivalent, ECD; endothelial cell density, IOP; intraocular pressure, CME; cystoid macular edema