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Putative chimeric proteins often contain the signal peptides or TM domains of the parental proteins. (A) Schematic view of the two proteins participating in the human chimera: thioredoxin domain containing protein 5 (TXNDC5) and lysophosphatidylcholine acyltransferase 2 (LPCAT2). (B) Schematic view of the hypothetical chimera comprising the signal peptide of TXNDC5 and two TM domains of LPCAT2. We predict that this chimera is localized in the ER lumen.
