Table 2.
Estimated Peppas parameters as a function of drug loading percentages and loading techniques
| Drug loading | In-situ drug loading | Freeze-drying drug loading | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Release rate constant (K, day−1) | Regression coefficient (R2) | Release index (n) | Release rate constant (K, day−1) | Regression coefficient (R2) | Release index (n) | |
| 2% 5-FU | 58.75 ± 4.32 | 0.87 | 0.23 ± 0.03 | 66.22 ± 2.94 | 0.91 | 0.18 ± 0.02 |
| 3% 5-FU | 56.78 ± 3.80 | 0.88 | 0.22 ± 0.03 | 67.39 ± 1.55 | 0.95 | 0.14 ± 0.01 |
| 5% 5-FU | 64.08 ± 1.93 | 0.92 | 0.14 ± 0.01 | 94.73 ± 1.55 | 0.96 | 0.15 ± 0.02 |
Abbreviation: 5-FU, 5-fluorouracil.