Table 1.
Demographic, Psychiatric, Substance Use, Medical, HIV Disease, and Cognitive Characteristics of the Study Groups.
| Variable | HIV − (n=87) |
HIV + (n=86) |
p-value |
|---|---|---|---|
| Demographic Characteristics | |||
| Age (years) | 43.4 (14.5) | 46.2 (13.4) | 0.202 |
| Education (years) | 14.1 (2.2) | 13.6 (2.7) | 0.247 |
| Sex (% Male) | 71.3% | 81.4% | 0.117 |
| Ethnicity (% Caucasian) | 58.6% | 55.8% | 0.709 |
| Estimated Verbal IQ a | 102.8 (9.1) | 99.8 (10.8) | 0.122 |
| NP Impairment (% impaired) | 19.5% | 34.9% | 0.023 |
| Psychiatric & Substance Use Characteristics | |||
| Total Mood Disturbance (POMS)b | 36.0 (22.0, 56.0) | 40.0 (23.0, 58.5) | 0.313 |
| Major Depressive Disorder (% lifetime) | 32.2% | 46.5% | 0.054 |
| Generalized Anxiety Disorder (% lifetime) | 3.5% | 9.3% | 0.115 |
| Substance Use Disorder (% lifetime) | 64.4% | 62.8% | 0.829 |
| Medical Characteristics | |||
| Hepatitis C Virus (%) | 10.3% | 23.5% | 0.021 |
| HIV Disease Characteristics | |||
| AIDS (%) | - | 45.3% | - |
| cART (%) | - | 88.4% | - |
| Plasma Viral Load (% detectable) | - | 22.6% | - |
| Nadir CD4 Count (cells/µL)b | - | 220.0 (119.5, 326.8) | - |
| Current CD4 Count (cells/µL)b | - | 568.0 (382.0, 775.0) | - |
| Cognitive Variables | |||
| Letter Fluency: B (raw) | 16.2 (4.7) | 14.1 (4.9) | 0.003 |
| Category Fluency: Clothing (raw) | 19.1 (4.7) | 16.8 (4.2) | <0.001 |
| Category Switchingc: Total Correct | 17.3 (2.9) | 15.2 (2.7) | <0.001 |
| Category Switchingc: Accurate Switches | 15.9 (3.8) | 14.0 (3.1) | <0.001 |
| BNT (Total Correct) | 53.4 (6.1) | 52.7 (6.6) | 0.493 |
Note. Data represent means and standard deviations unless otherwise noted;
a
Based on the Wechsler Test of Adult Reading;
b
Median (interquartile range).
c
Animals and musical instruments;
HIV = Human immunodeficiency virus. POMS = Profile of Mood Disturbance. AIDS = Acquired immune deficiency syndrome. cART = Combined antiretroviral therapy. CD4 = Cluster of differentiation 4. BNT = Boston Naming Test.