Table 2.

Human and mouse chemokine receptors

Human gene symbol	Other names	Category	Mouse gene symbol	Ligands
				Agonistic	Antagonistic
CXCR subfamily
CXCR1	IL8RA	I	Cxcr1	CXCL6, CXCL7, CXCL8, acPGP
CXCR2	IL8RB	I	Cxcr2	CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7, CXCL8, acPGP, MIF
CXCR3	GPR9	I	Cxcr3	CXCL4 (CXCR3-B), CXCL9, CXCL10, CXCL11, CXCL13 CCL21 (mouse)	CCL11
CXCR4	LESTER, Fusin	H	Cxcr4	CXCL12, MIF, ubiquitin
CXCR5	BLR1	H	Cxcr5	CXCL13
CXCR6	STRL33, BONZO	H	Cxcr6	CXCL16
CCR subfamily
CCR1	CC-CKR-1	I	Ccr1	CCL3, CCL3L1, CCL5 CCL7, CCL8, CCL13, CCL14 CCL15, CCL16, CCL23	CCL26
CCR2	CC-CKR-2	I	Ccr2	CCL2, CCL7, CCL8, CCL13 CCL16, β-defensin 2,3	CCL11, CCL26
CCR3	CC-CKR-3	I	Ccr3	CCL3L1, CCL5, CCL7, CCL11 CCL13, CCL14, CCL15, CCL24 CCL26, CCL28	CXCL9, CXCL10, CXCL11, CCL18
CCR4	CC-CKR-4	D	Ccr4	CCL17, CCL22
CCR5	CC-CKR-5	I	Ccr5	CCL3, CCL3L1, CCL4, CCL4L1 CCL5, CCL8, CCL11, CCL16	CCL7, CXCL11 CCL26
CCR6	STRL22, GPR29	I	Ccr6	CCL20, β-defensin-2
CCR7	EBI1, BLR2	H	Ccr7	CCL19, CCL21
CCR8	TER1, GPR-CY6	H	Ccr8	CCL1, CCL16, CCL8 (mouse)
CCR9	GPR-9-6	H	Ccr9	CCL25
CCR10	GPR2	H	Ccr10	CCL27, CCL28
XCR subfamily
XCR1	GPR-5	D	Xcr1	XCL1, XCL2
CX3CR subfamily
CX3CR1	V28, GPR13	D	Cx3cr1	CX3CL1, CCL26
Atypical (non-chemotactic, recycling or scavenger receptors)
CXCR7	RDC1, GPR159		Cxcr7	CXCL11, CXCL12
CCBP2	D6		Ccbp2	CCL2, CCL3, CCL3L1, CCL4, CCL4L1, CCL5, CCL7, CCL8, CCL11, CCL12, CCL13, CCL14 CCL17, CCL22, CCL23, CCL24
CCRL1	CCX-CKR		Ccrl1	CCL19, CCL21, CCL25, CXCL13
CCRL2	HCR, CRAM		Ccrl2	CCL19, chemerin
DARC	Duffy		Darc	CXCL1, CXCL2, CXCL3, CXCL7, and CXCL8, CCL2, CCL5, CCL11, CCL13, CCL14, CCL17

acPGP, N-acetyl Pro-Gly-Pro; MIF, macrophage migration inhibitory factor.