Table 3.
Distribution of subject scores according to clinical prediction rules, clinic-based cohort
| Total | No mutation |
With mutation |
|||||
|---|---|---|---|---|---|---|---|
| Characteristics | N | (%) | N | (%) | N | (%) | P value |
| PREM1,2,6 | |||||||
| <5% | 2 | (2) | 1 | (2) | 1 | (1) | |
| 5–9% | 5 | (4) | 3 | (6) | 2 | (2) | |
| 10–19% | 20 | (15) | 13 | (27) | 7 | (9) | |
| 20–29% | 19 | (15) | 10 | (20) | 9 | (11) | |
| 30–39% | 14 | (11) | 3 | (6) | 11 | (14) | |
| ≥40% | 69 | (53) | 19 | (39) | 50 | (63) | |
| Total | 129 | (100) | 49 | (100) | 80 | (100) | |
| Mean score (±SD) | 49 | (±29) | 39 | (±28) | 55 | (±29) | 0.001 |
| MMRpredict (proximal) | |||||||
| <0.5% | 0 | (0) | 0 | (0) | 0 | (0) | |
| 0.5–4% | 6 | (6) | 0 | (0) | 6 | (9) | |
| 5–19% | 18 | (18) | 5 | (16) | 13 | (19) | |
| 20–44% | 11 | (11) | 4 | (13) | 7 | (10) | |
| ≥45% | 64 | (65) | 22 | (71) | 42 | (62) | |
| Total | 99 | (100) | 31 | (100) | 68 | (100) | |
| MMRpredict (distal) | |||||||
| <0.5% | 2 | (2) | 0 | (0) | 2 | (3) | |
| 0.5–4% | 20 | (20) | 5 | (16) | 15 | (22) | |
| 5–19% | 20 | (20) | 6 | (19) | 14 | (21) | |
| 20–44% | 17 | (17) | 6 | (19) | 11 | (16) | |
| ≥45% | 40 | (41) | 14 | (45) | 26 | (38) | |
| Total | 99 | (100) | 31 | (100) | 68 | (100) | |
| Mean score (±SD) – proximal | 60 | (±35) | 64 | (±32) | 58 | (±36) | 0.41 |
| Mean score (±SD) – distal | 41 | (±36) | 44 | (±35) | 40 | (±37) | 0.65 |
| MMRpro | |||||||
| <5% | 9 | (7) | 5 | (10) | 4 | (5) | |
| 5–9% | 4 | (3) | 3 | (6) | 1 | (1) | |
| 10–19% | 9 | (7) | 6 | (12) | 3 | (4) | |
| 20–29% | 3 | (2) | 1 | (2) | 2 | (3) | |
| 30–39% | 5 | (4) | 1 | (2) | 4 | (5) | |
| ≥40% | 99 | (77) | 33 | (67) | 66 | (82) | |
| Total | 129 | (100) | 49 | (100) | 80 | (100) | |
| Mean score (±SD) | 74 | (±36) | 65 | (±40) | 79 | (±32) | 0.04 |