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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: J Inorg Biochem. 2011 Nov 27;108:105–111. doi: 10.1016/j.jinorgbio.2011.11.005

Fig. 2.

Fig. 2

Overall structural architecture of the biological unit of TGR from Schistosoma mansoni. The enzyme is a W-shaped homodimer, each monomer being the fusion of a Grx domain (in green) and a TrxR domain (in magenta and in blue). At the bottom of a large cavity lies the FAD cofactor (shown as a sphere). The C-terminal, Sec-containing arm of each TrxR subunit points towards the FAD binding site of the other.