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. 2012 Jul 13;7(7):e40649. doi: 10.1371/journal.pone.0040649

Figure 4. The sequence logos of three conserved motifs in subgroups of HES/HEY genes.

Figure 4

The Motif 1 was created using an alignment of HEY1/2/L sequences near bHLH domain. The similar process was used to get Motif 2 (DEC1/2 sequence near Orange domain) and Motif 3 (DEC1 sequence in C-terminal). The overall height of each stack indicates the sequence conservation at that position, whereas the height of symbols within each stack reflects the relative frequency of the corresponding amino acid.