Table 3. Hepatocyte nuclear factors are associated with Slc22 genes in silico and in vitro.
Gene | In vitro or in silico experiment |
Oat1 | Promoter analysis [51] |
In vitro regulation [58] | |
In vitro regulation [59] | |
Oat3 | Promoter analysis [51] |
Oct1 | Promoter analysis, in vitro regulation [60] |
Evidence from the literature demonstrates the potential for functional regulation of the SLC22 family of genes by hepatocyte nuclear factors.