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. 2012 Jul 13;7(7):e40658. doi: 10.1371/journal.pone.0040658

Table 1. IgM linked SerpinB3 and SerpinB4 isoforms, compared to total SCCA-IgM in patients with different extent of chronic liver disease.

Chronic hepatitis Cirrhosis HCC Healthy Subjects
n = 17 n = 36 n = 26 n = 28
SerpinB3-IgM (SCC111) Median (OD405 nm) 0.130 0.130 0.130 0.130
IQR 0.130–0.172 0.130–0.221 0.130–0.175 0.130–0.130
95th percentile 0.200
% positivity 12 28 23 7
SerpinB4-IgM (SCC103) Median (OD405 nm) 0.207 0.168 0.140 0.154
IQR 0.140–0.275 0.140–0.427 0.140–0.278 0.140–0.249
95th percentile 0.384
% positivity 12 28 23 7
SerpinB4-IgM (SCC104) Median (OD405 nm) 0.126 0.135 0.125 0.125
IQR 0.125–0.227 0.125–0.285 0.125–0.319 0.125–0.125
95th percentile 0.199
% positivity 29 42 35 7
Total SCCA-IgM Median (AU/mL) 166 134 209 115
IQR 80–511 80–552 118–287 109–129
95th percentile 156
% positivity 53 47 58 0

IQR = interquartile range (25th–75th percentile).

The percentage of positivity for each immunocomplex was determined as the fraction number of patients with immunocomplex levels above the defined cut-off value (95th percentile).