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. 2012 Jul 13;7(7):e40794. doi: 10.1371/journal.pone.0040794

Figure 6. Effect of enzyme inhibitors on average tumor volume and tumor growth rate of MDA-MB-231 tumor xenografts.

Figure 6

Comparison of average tumor volume (A) and tumor growth rate (B) of MDA-MB-231 tumor xenografts treated with either vehicle or roziglitazone, or zileuton, or ibuprofen alone or a combination of the three inhibitors at doses described in Materials and Methods. Values are mean ± SD, n = 5. The characters indicate significant differences between tumor volume and rate of tumor growth by one-way ANOVA, post test Bonferroni. a, P<0.001 vs vehicle; b, P<0.001 vs rosiglitazone; c, P<0.001 vs zileuton; d, P<0.01 vs ibuprofen.