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. 2012 Jul 13;7(7):e40917. doi: 10.1371/journal.pone.0040917

Table 1. Association of socioeconomic status with other potential prognostic variables among persons diagnosed with hepatocellular carcinoma, 1990–2009.

Variable Income Quintile 1N (%) Income Quintile 2N (%) Income Quintile 3N (%) Income Quintile 4N (%) Income Quintile 5N (%) MissingN (%) p-value*
N  = 1323 N  = 1196 N  = 1030 N  = 915 N  = 893 N = 124
Age group
 60 or below 526 (39.7) 424 (35.4) 378 (36.7) 320 (35.0) 295 (33.0) 40 (32.3)
 61–70 369 (27.9) 387 (32.4) 285 (27.7) 274 (30.0) 270 (30.2) 48 (38.7)
 71–80 333 (25.2) 312 (26.1) 287 (27.9) 253 (27.6) 265 (29.7) 26 (21.0)
 81 or above 95 (7.2) 73 (6.1) 80 (7.7) 68 (7.4) 63 (7.1) 10 (8.0) 0.0532
Sex (male) 1020 (77.1) 931 (77.8) 809 (78.5) 722 (78.9) 713 (79.8) 84 (67.7) 0.5988
Rurality
 Urban residence 1215 (91.8) 1110 (92.8) 937 (91.0) 831 (90.8) 821 (91.9) 16 (12.9)
 Rural residence 108 (8.2) 86 (7.2) 93 (9.0) 84 (9.2) 72 (8.1) 6 (4.8)
 Missing 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 102 (82.3) 0.4497
Country of birth
 Canada 423 (32.0) 388 (32.4) 343 (33.3) 306 (33.4) 325 (36.4) 60 (48.4)
 Outside Canada 582 (44.0) 500 (41.8) 421 (40.9) 374 (40.9) 331 (37.1) 51 (41.1)
 Missing 318 (24.0) 308 (25.8) 266 (25.8) 235 (25.7) 237 (26.5) 13 (10.5) 0.1766
Maximum Charlson Comorbidity score
 0 499 (37.7) 444 (37.1) 383 (37.2) 350 (38.2) 334 (37.4) 54 (43.5)
 1 290 (21.9) 264 (22.1) 202 (19.6) 182 (19.9) 182 (20.4) 29 (23.4)
 2 165 (12.5) 128 (10.7) 130 (12.6) 123 (13.4) 114 (12.8) 15 (12.1)
 3 or more 141 (10.7) 110 (9.2) 98 (9.5) 72 (7.9) 80 (9.0) 9 (7.3)
 No hospitalization record 228 (17.2) 250 (20.9) 217 (21.1) 188 (20.6) 183 (20.5) 17 (13.7) 0.3279
Screening with ultrasound 1 year prior to HCC diagnosis 388 (29.3) 355 (29.7) 319 (31.0) 291 (31.8) 283 (31.7) 6 (4.8) 0.6148
HCC treatment
 Curative 335 (25.3) 365 (30.5) 336 (32.6) 294 (32.1) 288 (32.3) 19 (15.3) 0.0003
 Non-curative 184 (13.9) 203 (17.0) 185 (18.0) 160 (17.5) 147 (16.5) 11 (8.9) 0.0637
 Palliative 485 (36.7) 410 (34.3) 360 (35.0) 333 (36.4) 309 (34.6) 9 (7.3) 0.6798
 No treatment 517 (39.1) 438 (36.6) 347 (33.8) 324 (35.4) 319 (35.7) 89 (71.8) 0.0936
Year of HCC diagnosis
 1990–1994 156 (11.8) 146 (12.2) 111 (10.8) 94 (10.3) 104 (11.6) 105 (84.7)
 1995–1999 252 (19.0) 239 (20.0) 196 (19.0) 180 (19.7) 172 (19.3) - (3.2)
 2000–2004 395 (29.9) 329 (27.5) 310 (30.1) 273 (29.8) 259 (29.0) - (3.2)
 2005–2009 520 (39.3) 482 (40.3) 413 (40.1) 368 (40.2) 358 (40.1) 11 (8.9) 0.9679

Income quintile 1, lowest socioeconomic status; Income quintile 5, highest socioeconomic status.

“-“, counts less than five have been suppressed. *p-values were calculated using chi-squared tests, testing for homogeneity across all income groups, excluding the missing groups. Patients were not considered as being screened if they had only one ultrasound in the three months prior to diagnosis or if they were receiving HCC care prior to the ultrasound. Included multiple treatments for some people. HCC, hepatocellular carcinoma.