| BLAD |
Participation in GWAS for bladder cancer |
Nested case control study aimed at identifying novel genetic variants which are worthy of intensive pursuit in epidemiological, genetic mapping, clinical and laboratory investigationson bladder cancer. |
950 |
| BRCD |
Participation in the Breast an Prostate Cancer Cohort Consortium (BPC3) – Breast cancer component |
Nested case-control study aimed at the analysis of genes related to steroid hormone and insulin-like growth factor-1 metabolism and breast cancer risk in EPIC which is part of theNCI breast and prostate cancer cohort consortium and GWAS study of ER-negativebreast cancer. |
8071 |
| CORD |
The Influence of Vitamin D andPolymorphisms of the Vitamin D Receptorand Calcium Sensing Receptoron Colorectal Cancer Risk |
Nested case-control study aimed at evaluating the roles of both vitamin-D (important in calcium homeostasis/cell cycle kinetics) and calcium (role in cell cycle kinetics) incolorectal cancer prevention. |
2177 |
| EGAD |
Genetic susceptibility, environmental factors and the gastric cancer risk in European populations (EUR-GAST II) |
Nested case-control study aimed at (a) evaluating the effect of dietary and environmental exposures by histological and anatomical subtypes of gastric cancer; (b) evaluating theeffect of dietary and environmental factors on esophageal adenocarcinomas; (c) evaluatingthe main effect of genetic polymorphisms in several candidates genes. |
1444 |
| EPHD |
Study of the interplay of genetic, biochemical and lifestyle factors in coronary heart disease (EPIC-HEART) |
Nested case-control study aimed at investigating the separate and combined influencesof genetic, biochemical and major lifestyle factors (notably diet) on the incidence ofcoronary heart disease (CHD). |
7643 |
| HPVD |
HPV and cervical: the role of diet,environmental and infectiouscofactors, and genetic susceptibility |
Nested case-control study aimed at evaluating the association between serological markersof HPV infection and cervical cancer as well as the role in cervical carcinogenesis of: (a) environmental cofactors (diet, tobacco, parity, use of hormonal contraceptives),(b) infectious cofactors (HSV-2 and C. trachomatis); and (c) markers of geneticsusceptibility. |
664 |
| INTD |
Examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes (INTERACT) |
Nested case-control study aimed at evaluating gene-lifestyle interactions in relationwith type 2 diabetes. |
18439 |
| KIDD |
Genome Wide Association Study of kidney cancer |
The aims of this study are to (i) immediately replicate approximately the top 30 variants in a large follow-up series, and (ii) substantially replicate between 20,000 and 317,000 variants following the GWAS of kidney cancer recently completed involving 1400 cases and 2800 controls from an IARC Central Europe study. |
792 |
| LUND |
DNA methylation changes associated with cancer risk factors and blood levels ofvitamin metabolites |
The aim of this study is to investigate the contribution of common human genetic variationto susceptibility of lung cancer. The association between lung cancer and DNA methylation patterns in a panel of candidate genes is examined. It is also investigated whether bloodlevels of vitamin metabolites modify DNA methylation levels in blood cells. DNAmethylation levels are quantitatively determined in blood cells of nestedcases and controls. |
2450 |
| LYMD |
EPIC Nested case-control investigation on lymphomas |
Nested case-control study aimed at elucidating whether risk factors for lymphoma exerttheir effect by modulation of the immune system by studying the inherited andacquired immune response in non-Hodgkin lymphoma (NHL) cases and controls. |
1789 |
| PAND |
Genome Wide association Study andpancreatic cancer (PanScan) |
Nested case-control study aimed at conducting a whole genome scan (WGS) of common genetic variants to identify genetic markers of susceptibility to pancreatic cancer. |
504 |
| PROD |
Participation in the Breast an Prostate Cancer Cohort Consortium (BPC3) – Prostate cancer component |
Nested case-control study aimed at the analysis of genes related to steroid hormone and insulin-like growth factor-1 metabolism and prostate cancer risk in EPIC which is part ofthe NCI breast and prostate cancer cohort consortium and GWAS study of aggressiveprostate cancer. |
2238 |
