Table 3. Effects of individual characteristics and processing variations on DNA yield (µg).
| Estimated coefficientfor effect(c) | SE | P value | |
| Gender | |||
| Men | reference | ||
| Women | 1.437 | 0.388 | <0.01 |
| Age | −0.107 | 0.020 | <0.01 |
| BMI | 0.390 | 0.039 | <0.01 |
| Tobacco consumption | |||
| Never smoker | reference | ||
| Former smoker | 0.366 | 0.375 | 0.33 |
| Current smoker | 10.871 | 0.515 | <0.01 |
| Incident cancer | |||
| No | reference | ||
| Yes | 2.494 | 0.363 | <0.01 |
| Previous cancer | |||
| No | reference | ||
| Yes | 1.252 | 1.157 | 0.28 |
| Number of straws used | |||
| One straw | reference | ||
| Two straws | 30.276 | 0.489 | <0.01 |
| Extraction method | |||
| Autopure LS 1 | reference | ||
| Autopure LS 2 | −2.439 | 0.434 | <0.01 |
| Manual | −6.757 | 0.994 | <0.01 |
| Quantification method | |||
| Nanodrop | reference | ||
| Picogreen | 6.449 | 0.516 | <0.01 |
| Haemolysis | |||
| No | reference | ||
| Yes | −7.895 | 0.814 | <0.01 |
| Haemolysis | |||
| Light haemolysis | reference | ||
| Medium haemolysis | −5.370 | 1.685 | <0.01 |
| Heavy haemolysis | −9.509 | 9.221 | 0.30 |
| Time from collection to refrigeration (per 30 minutes) | 0.482 | 0.213 | 0.02 |
| Time from refrigeration to centrifugation (per 30 minutes) | 0.227 | 0.036 | <0.01 |
| Time from centrifugation to freezing (per 30 minutes) | 0.057 | 0.138 | 0.68 |
| Time from blood collection to incident cancer diagnosis (per year) | −0.138 | 0.116 | 0.24 |
| Time from prevalent cancer diagnosis to blood collection (per year) | 0.358 | 0.165 | 0.03 |
c
The estimated coefficients for effect reflect the increasing (positive value) or decreasing (negative value) concentration response to the lifestyle/exposure factor, adjusted for the other lifestyle/exposure factors.