Table 3.
Primate-specific GO term enrichment of the four gene classes.
| Class | GO code | GO name | Human | Orangutan | Macaque |
|---|---|---|---|---|---|
| TS | GO:0005201 | Extracellular matrix structural constituent | * | – | – |
| TS | GO:0031965 | Nuclear membrane | * | – | – |
| TS | GO:0008360 | Regulation of cell shape | * | – | – |
| T | GO:0019882 | Antigen processing and presentation | * | – | – |
| T | GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | * | – | – |
| T | GO:0002504 | Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | * | – | – |
| T | GO:0004004 | ATP-dependent RNA helicase activity | * | – | – |
| T | GO:0005125 | Cytokine activity | – | * | – |
| T | GO:0022625 | Cytosolic large ribosomal subunit | * | – | – |
| T | GO:0010008 | Endosome membrane | * | – | – |
| T | GO:0004308 | Exo-alpha-sialidase activity | * | – | – |
| T | GO:0031640 | Killing of cells of another organism | * | – | – |
| T | GO:0005765 | Lysosomal membrane | * | – | – |
| T | GO:0042613 | MHC class II protein complex | * | – | – |
| T | GO:0032395 | MHC class II receptor activity | * | – | – |
| T | GO:0005763 | Mitochondrial small ribosomal subunit | * | – | – |
| T | GO:0000398 | Nuclear mRNA splicing, via spliceosome | * | – | – |
| T | GO:0005730 | Nucleolus | * | – | – |
| T | GO:0019887 | Protein kinase regulator activity | * | – | – |
| T | GO:0003723 | RNA binding | * | – | – |
| T | GO:0008380 | RNA splicing | * | – | – |
| T | GO:0019843 | rRNA binding | * | – | – |
| T | GO:0005681 | Spliceosomal complex | * | – | – |
| T | GO:0006414 | Translational elongation | * | – | – |
| T | GO:0017070 | U6 snRNA binding | * | – | – |
| S | GO:0004869 | Cysteine-type endopeptidase inhibitor activity | – | * | – |
| S | GO:0044424 | Intracellular part | – | – | * |
| S | GO:0045665 | Negative regulation of neuron differentiation | * | – | – |
| S | GO:0009887 | Organ morphogenesis | * | – | – |
| S | GO:0002876 | Positive regulation of chronic inflammatory response to antigenic stimulus | * | – | – |
| S | GO:0002925 | Positive regulation of humoral immune response mediated by circulating immunoglobulin | * | – | – |
| S | GO:0010843 | Promoter binding | * | – | – |
| S | GO:0007519 | Skeletal muscle tissue development | – | * | – |
| S | GO:0005164 | Tumor necrosis factor receptor binding | * | – | – |
| N | GO:0002474 | Antigen processing and presentation of peptide antigen via MHC class I | * | – | – |
| N | GO:0007267 | Cell-cell signaling | * | – | – |
| N | GO:0009987 | Cellular process | * | – | – |
| N | GO:0010467 | Gene expression | * | – | – |
| N | GO:0008201 | Heparin binding | * | – | – |
| N | GO:0042309 | Homoiothermy | – | – | * |
| N | GO:0050825 | Ice binding | – | – | * |
| N | GO:0048535 | Lymph node development | * | – | – |
| N | GO:0032393 | MHC class I receptor activity | * | – | – |
| N | GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | – | – | * |
| N | GO:0048663 | Neuron fate commitment | * | – | * |
| N | GO:0005184 | Neuropeptide hormone activity | * | – | – |
| N | GO:0004522 | Pancreatic ribonuclease activity | * | – | – |
| N | GO:0010552 | Positive regulation of gene-specific transcription from RNA polymerase II promoter | – | – | * |
| N | GO:0045084 | Positive regulation of interleukin-12 biosynthetic process | * | – | – |
| N | GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | – | – | * |
| N | GO:0050826 | Response to freezing | – | – | * |
| N | GO:0016471 | Vacuolar proton-transporting V-type ATPase complex | * | – | – |
Note: The asterisks indicate significant enrichment of GO terms.