Table 5.
Rodent-specific GO term enrichment of the four gene classes.
| Class | GO code | GO name | Mouse | Rat | Guinea pig |
|---|---|---|---|---|---|
| TS | GO:0015629 | Actin cytoskeleton | * | – | – |
| TS | GO:0008415 | Acyltransferase activity | – | * | – |
| TS | GO:0045177 | Apical part of cell | * | – | – |
| TS | GO:0006915 | Apoptosis | * | – | – |
| TS | GO:0030424 | Axon | * | * | – |
| TS | GO:0008013 | Beta-catenin binding | – | * | – |
| TS | GO:0005975 | Carbohydrate metabolic process | * | – | – |
| TS | GO:0007049 | Cell cycle | * | * | – |
| TS | GO:0051301 | Cell division | * | – | – |
| TS | GO:0042995 | Cell projection | * | – | – |
| TS | GO:0009986 | Cell surface | * | * | – |
| TS | GO:0016568 | Chromatin modification | * | – | – |
| TS | GO:0000777 | Condensed chromosome kinetochore | * | – | – |
| TS | GO:0016023 | Cytoplasmic membrane-bounded vesicle | – | * | – |
| TS | GO:0031410 | Cytoplasmic vesicle | * | * | – |
| TS | GO:0030425 | Dendrite | – | * | – |
| TS | GO:0006281 | DNA repair | * | * | – |
| TS | GO:0009055 | Electron carrier activity | * | – | – |
| TS | GO:0005768 | Endosome | * | * | – |
| TS | GO:0009897 | External side of plasma membrane | – | * | – |
| TS | GO:0031012 | Extracellular matrix | – | * | – |
| TS | GO:0005925 | Focal adhesion | – | * | – |
| TS | GO:0005525 | GTP binding | * | – | – |
| TS | GO:0005096 | GTPase activator activity | * | * | – |
| TS | GO:0004386 | Helicase activity | * | – | – |
| TS | GO:0042802 | Identical protein binding | * | * | – |
| TS | GO:0030027 | Lamellipodium | * | – | – |
| TS | GO:0016042 | Lipid catabolic process | * | – | – |
| TS | GO:0042470 | Melanosome | – | * | – |
| TS | GO:0008168 | Methyltransferase activity | * | – | – |
| TS | GO:0005874 | Microtubule | * | – | – |
| TS | GO:0008017 | Microtubule binding | * | – | – |
| TS | GO:0005739 | Mitochondrion | * | * | – |
| TS | GO:0007067 | Mitosis | * | – | – |
| TS | GO:0006397 | mRNA processing | – | * | – |
| TS | GO:0043066 | Negative regulation of apoptosis | – | * | – |
| TS | GO:0043025 | Neuronal cell body | – | * | – |
| TS | GO:0005634 | Nucleus | * | * | – |
| TS | GO:0030165 | PDZ domain binding | – | * | – |
| TS | GO:0048471 | Perinuclear region of cytoplasm | * | * | – |
| TS | GO:0005777 | Peroxisome | * | * | – |
| TS | GO:0035091 | Phosphoinositide binding | * | – | – |
| TS | GO:0043065 | Positive regulation of apoptosis | – | * | – |
| TS | GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB cascade | * | – | – |
| TS | GO:0014069 | Postsynaptic density | – | * | – |
| TS | GO:0006813 | Potassium ion transport | * | – | – |
| TS | GO:0042734 | Presynaptic membrane | – | * | – |
| TS | GO:0043234 | Protein complex | * | * | – |
| TS | GO:0032403 | Protein complex binding | * | * | – |
| TS | GO:0019904 | Protein domain specific binding | – | * | – |
| TS | GO:0046982 | Protein heterodimerization activity | – | * | – |
| TS | GO:0019901 | Protein kinase binding | – | * | – |
| TS | GO:0008104 | Protein localization | – | * | – |
| TS | GO:0008565 | Protein transporter activity | * | – | – |
| TS | GO:0016567 | Protein ubiquitination | * | * | – |
| TS | GO:0045449 | Regulation of transcription | * | – | – |
| TS | GO:0006974 | Response to DNA damage stimulus | – | * | – |
| TS | GO:0042493 | Response to drug | – | * | – |
| TS | GO:0001666 | Response to hypoxia | – | * | – |
| TS | GO:0007584 | Response to nutrient | – | * | – |
| TS | GO:0014070 | Response to organic cyclic substance | – | * | – |
| TS | GO:0004871 | Signal transducer activity | * | * | – |
| TS | GO:0005625 | Soluble fraction | * | * | – |
| TS | GO:0015293 | Symporter activity | – | * | – |
| TS | GO:0019717 | Synaptosome | * | * | – |
| TS | GO:0005802 | Trans-Golgi network | * | – | – |
| TS | GO:0006511 | Ubiquitin-dependent protein catabolic process | * | – | – |
| TS | GO:0004842 | Ubiquitin-protein ligase activity | – | * | – |
| S | GO:0009653 | Anatomical structure morphogenesis | – | * | – |
| S | GO:0001658 | Branching involved in ureteric bud morphogenesis | * | – | – |
| S | GO:0045165 | Cell fate commitment | * | * | – |
| S | GO:0042733 | Embryonic digit morphogenesis | * | – | – |
| S | GO:0060441 | Epithelial tube branching involved in lung morphogenesis | * | – | – |
| S | GO:0042472 | Inner ear morphogenesis | * | – | – |
| S | GO:0003676 | Nucleic acid binding | – | * | – |
| S | GO:0048709 | Oligodendrocyte differentiation | * | – | – |
| S | GO:0001569 | Patterning of blood vessels | * | – | – |
| S | GO:0005550 | Pheromone binding | * | – | – |
| S | GO:0008284 | Positive regulation of cell proliferation | * | – | – |
| S | GO:0010552 | Positive regulation of gene-specific transcription from RNA polymerase II promoter | * | – | – |
| S | GO:0045666 | Positive regulation of neuron differentiation | * | * | – |
| S | GO:0010468 | Regulation of gene expression | * | * | – |
| S | GO:0048536 | Spleen development | – | * | – |
| S | GO:0030878 | Thyroid gland development | * | – | – |
| S | GO:0016564 | Transcription repressor activity | * | – | – |
| N | GO:0006935 | Chemotaxis | * | – | – |
| N | GO:0001533 | Cornified envelope | * | – | – |
| N | GO:0006952 | Defense response | * | – | – |
| N | GO:0042742 | Defense response to bacterium | * | – | – |
| N | GO:0005615 | Extracellular space | * | * | – |
| N | GO:0006954 | Inflammatory response | * | * | – |
| N | GO:0007389 | Pattern specification process | – | * | – |
| N | GO:0004252 | Serine-type endopeptidase activity | – | * | – |
Note: The asterisks stand for significant enrichment of GO terms.