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. 2012 Jul 13;7(7):e39392. doi: 10.1371/journal.pone.0039392

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Sato, Ikegami.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Lung compliance of the preterm newborn lamb was improved by both CHF5633 and Survanta treatment. Overall compliance after treatment was not significantly different between CHF5633 and Survanta group (p>0.05 by two-way repeated measures ANOVA). Compliance was higher for CHF5633 than Survanta group at 20 min and 300 min of age (*p<0.04 by t-test). (B) The overall deflation limbs of pressure-volume curves were similar between CHF5633 group and Survanta group (p>0.05 by two-way repeated measures ANOVA). The volume at 10 cmH₂O was higher for CHF5633 group than Survanta group (*p<0.05 by t-test).