Figure 9. Surfactant ultrastructure.

(A) CHF5633. Ultrastructure of CHF5633 Input was extremely large with ball bearing like form. In the supernatant of the BALF, ultrastructure of small aggregate of CHF5633 was lipid layers with various forms. The recovered CHF5633 in the pellet from BALF were large, softly aggregated lipid particles. (B.) Ultrastructure of Survanta was simple lipid layers that were changed to small lipid vesicle or lamellated structure in the preterm lamb lung. (C.) Air group or Endogenous Surfactant. In the extremely preterm lamb lung airways, small amounts of surfactant with normal ultrastructure including lamellar bodies and tubular myelin were present. Scale bar: 2 µm: Scale bar in inset: 0.5 µm.