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. 2012 Jul 13;7(7):e40589. doi: 10.1371/journal.pone.0040589

Figure 4. VEGF knockdown induces proteinuria and acute renal failure.

Figure 4

(A) Immunoblot shows severe albuminuria in VEGF Knockdown mice. (B) ELISA: urinary albumin/creatinine ratio in VEGF knockdown mice is 10-fold higher than in controls. (C) Creatinine clearance is 62% lower in VEGF knockdown mice than in controls. (D) Plasma creatinine significantly increases in VEGF knockdown mice. * indicates P<0.05 vs. control.