Table 2. Competitive Indices of mixed infections using the WT, ΔSTM1485 and the pQE601485 complemented strains.
|
Strain-1 |
Strain-2 |
Competitive index of strain 2 with respect to strain 1 |
||
---|---|---|---|---|---|
Spleen | Liver | MLN¶ | |||
1 |
WT# |
WT§ |
1.121 ± 0.12 |
0.975 ± 0.17 |
1.124 ± 0.09 |
2 |
WT# |
ΔSTM1485 |
0.413 ± 0.05** |
0.341 ± 0.07** |
0.206 ± 0.13** |
3 | WT# | pQE601485 | 1.035 ± 0.14 | 1.367 ± 0.09 | 1.107 ± 0.12 |
# Resistant to nalidixic acid and the parent strain for knock out.
§ Resistant to Carbencillin. Both WT strains were isogenic.
¶ Mesentric lymph nodes.
p < 0.005 (Student's t-test); statistical difference between 1 and 2.