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Two secondary active cation-Cl− cotransporters expressed in GABA-responsive neurons. NKCC1 is an isoform of the Na+-K+-2Cl− cotransporter and KCC2 is an isoform of the K+-Cl− cotransporter; [Cl−]i is intracellular Cl− concentration. From Delpire E (2000). Cation-Chloride Cotransporters in Neuronal Communication. News Physiol Sci 15, 309–312, with permission.
