Table 2.

Associations of Categories of 25-hydroxyvitamin D Concentration With Small-for-Gestational Age (vs. Appropriate-for-Gestational Age), Data From 1067 White and 236 Black Mother/Infant Pairs Enrolled in Project Viva.

Category of Second Trimester Plasma 25(OH)D (nmol/L) n=1113	n(SGA)/n	Model 1 (unadjusted) OR [95% CI]	Model 2^a OR [95% CI]	Model 3^b OR [95% CI]

<25	7/47	4.10 [1.63, 10.28]	4.42 [1.60, 12.23]	3.63 [1.24, 10.60]
25-<50	18/314	1.46 [0.77, 2.78]	1.51 [0.78, 2.92]	1.43 [0.73, 2.79]
50-<75	22/543	1.0 [reference]	1.0 [reference]	1.0 [reference]
≥75	6/229	0.61 [0.24, 1.53]	0.61 [0.24, 1.55]	0.62 [0.24, 1.56]
<25 vs. ≥25		3.93 [1.65, 9.34]	3.94 [1.51, 10.29]	3.17 [1.16, 8.63]
Category of Cord Plasma 25(OH)D (nmol/L) n=734	n(SGA)/n	Model 1 [unadjusted] OR [95% CI]	Model 2^a OR [95% CI]	Model 3^b OR [95% CI]

<25	9/84	5.11 [1.75, 14.90]	6.19 [1.82, 21.07]	4.84 [1.33, 17.66]
25-<50	9/337	1.18 [0.42, 3.38]	1.16 [0.40, 3.38]	1.07 [0.36, 3.16]
50-<75	6/261	1.0 [reference]	1.0 [reference]	1.0 [reference]
≥75	1/52	0.84 [0.10, 7.20]	0.85 [0.10, 7.38]	0.87 [0.10, 7.61]
<25 vs. ≥25		4.72 [2.00, 11.12]	5.68 [2.07, 15.56]	4.64 [1.61, 13.36]

Abbreviations: 25(OH)D, 25-nydroxyvitamin D; OR, odds ratio; CI, confidence interval; SGA, small-tor-gestational age

Adjusted for season of blood draw, maternal age and pre-pregnancy BMI;

Model 2 + adjustment for race