. Author manuscript; available in PMC: 2012 Jul 14.

Published in final edited form as: J Pharmacol Sci. 2012 May 22;119(2):131–138. doi: 10.1254/jphs.12031fp

Table 1.

Changes in blood pressure, body weight, blood glucose, and renal renin mRNA expression

		C57BL	Vehicle	Val-Val15	Val-Val50	Val-Val+Ali
	baseline	93 ± 3	111 ± 3^*	110 ± 4^*	113 ± 2^*	108 ± 5^*
SBP (mmHg)	week 4	94 ± 3	120 ± 2^*	121 ± 6^*	119 ± 4^*	119 ± 4^*
	week 10	97 ± 3	129 ± 2^*	128 ± 3^*	109 ± 4^#	86 ± 3^#

	baseline	27.6 ± 0.4	42.9 ± 1.0^*	40.8 ± 0.7^*	42.6 ± 0.9^*	41.4 ± 0.8^*
BW (g)	week 4	28.9 ± 0.5	48.1 ± 1.1^*	45.3 ± 0.7^*	47.4 ± 1.1^*	47.4 ± 0.7^*
	week 10	30.8 ± 0.6	49.6 ± 0.8^*	50.2 ± 1.0^*	52.5 ± 1.3^*	47.3 ± 1.8^*

	baseline	125 ± 4	386 ± 25^*	431 ± 23^*	444 ± 25^*	423 ± 44^*
BG (mg/dL)	week 4	117 ± 4	448 ± 19^*	411 ± 30^*	460 ± 29^*	496 ± 14^*
	week 10	123 ± 5	487 ± 16^*	449 ± 16^*	454 ± 39^*	216 ± 32^*^#

Renin (fold)	week 10	1.00 ± 0.10	1.02 ± 0.11	1.54 ± 0.14	1.67 ± 0.08^*	3.06 ± 0.28^*^#

All data are expressed as relative differences to vehicle-infused rats after normalization for β-actin expression and are shown as means ± S.E.M.

P < 0.05 vs. C57BL mice.

P < 0.05 vs. vehicle group.

SBP: systolic blood pressure, BW: body weight, BG: blood glucose.