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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Traffic. 2012 May 8;13(8):1072–1082. doi: 10.1111/j.1600-0854.2012.01368.x

Fig.2. Distribution of CFTR and F-actin in major intestinal segments of WT129 and Myo1a KO mice.

Fig.2

A. CFTR (green) staining is shown in relation to F-actin (red), nuclei are stained in blue. Brush border localization for CFTR is indicated with filled arrowheads throughout the WT129 intestine and in the Myo1a KO colon. Redistribution of CFTR staining in the small intestine of Myo1a KO is indicated with empty arrows (BL) and empty arrowheads (SA). L, lumen of intestine. B. Quantification analysis of changes in CFTR distribution. Data are presented as means of percent of total intracellular CFTR in BB, SA or BL compartments. WT BB, 46.2±5.9; WT SA, 44.1±3.9; WT BL, 9.7±2.3; KO BB, 11.9±1.7; KO SA, 60±6.1; KO BL, 28.2±5.1. C. Average distance (um) of CFTR staining extending from the lumen into the subapical domain of villus enterocytes in WT and Myo1KO.