Skip to main content
. Author manuscript; available in PMC: 2013 Apr 1.
Published in final edited form as: Kidney Int. 2012 Apr 11;82(8):857–866. doi: 10.1038/ki.2012.104

Figure 2.

Figure 2

Figure 2

Tacrolimus (TAC) treatment or genetic deletion of FKBP12 from endothelial cells caused renal arteriolar hyalinosis. H&E staining (top panels) and Masson’s trichrome staining (bottom panels) reveal hyalinosis seen as the pink, glassy area indicated by the arrows in (A) TAC-treated mice (10 mg/kg/day; 1 week) and in (B) FK12EC KO mice compared to controls. Images at 400x final magnification. Quantification of arteriolar hyalinosis was determined using a scoring system previously described.7 n=6 mice/experimental group; *p<0.05 vs. control.