Table 2.

Factors Associated With Frequency and Severity of Nausea in Cycle 1

Factor	Present		Absent		Significance	Rating				Signficance*
	No.	%	No.	%		Mean	Median	Mode	SD
Sex					χ2 = 5.6; P = .0178†					Test statistic = 1,053.0; P < .001†‡
Male	12	34.29	23	65.71		0.38	0.00	0.00	0.60
Female	18	64.29	10	35.71		1.19	2.00	2.00	0.92
Transgendered	1	100.0	0	0.0		2.00	2.00	2.00	—
Total	31		33			0.76	0.0	0.0	0.86
History of motion sickness					.7039§					Test statistic = 250.5; P = .5473‖
Yes	4	57.14	3	42.86		1.00	1.00	0.0	1.00
No	27	47.37	30	52.63		0.73	0.0	0.0	0.85.
Total	31		33			0.76	0.0	0.0	0.86
History of morning sickness					1.000§					Test statistic = 181.00‡; P = .7505‖
Yes	8	61.54	5	38.46		1.23	2.00	2.00	1.01
No	9	64.29	5	35.71		1.15	1.00	2.00	0.90
Missing	1	100.0	0	0.0
Total	18		10
History of chemotherapy					.0245§					Test statistic = 364.5; P = .0108‖
Yes	7	87.50	1	12.50		1.50	2.00	2.00	0.76
No	24	42.86	32	57.14		0.65	0.0	0.0	0.83
Total	31		33			0.76	0.0	0.0	0.86
Nausea with prior chemotherapy					1.000§					Test statistic = 11.0; P = .4643‖
Yes	4	80.00	1	20.00		1.60	2.00	2.00	0.89
No	3	100.00	0	0.0		1.33	1.00	1.00	0.58
Total	7		1
Any prior nausea					χ2 = 2.2; P = .1361					Test statistic = 889.5; P = .0098‖
Yes	14	60.87	9	39.13		1.17	2.0	2.0	0.98
No	17	41.46	24	58.54		0.51	0.0	0.0	0.68
Total	31		33
Antinausea regimen					χ2 = 0.3; P = .85					Test statistic = 379.5; P = .61‖
Standard 5-HT3 inhibitor regimen	25	49.0	26	51.0		0.80	0.0	0.0	0.89
Standard plus aprepitant	6	46.2	7	53.9		0.62	0.0	0.0	0.77
Total	31		33
Regimen including palonosetron					χ2 = 4.04; P = .04					Test statistic = 832.0; P = .09‖
No	20	60.6	13	39.4		0.94	1.0	0.0	0.88
Yes	11	35.5	20	64.5		0.57	0.0	0.0	0.82
Total	31		33

Abbreviations: 5-HT₃, serotonin; SD, standard deviation.

^*Wilcoxon rank sums.

^†Transgendered dropped from significance testing.

^‡Exact probability, one sided.

^§Fisher's exact test, two sided.

^‖Exact probability, two sided.