Table 2.
Upregulation of Expression of Extracellular Matrix and Cell Adhesion Molecules in H9 Cells Grown on Polyester Membrane Substrate
| Gene title | Gene ID | Fold changea | p-Value |
|---|---|---|---|
| CD44 molecule | CD44 | 5.0 | 0.039 |
| Cadherin 1, type I | CDH1 | 2.9 | 0.025 |
| Collagen type XI, α1 | COL11A1 | 6.8 | 0.016 |
| Collagen type XII, α1 | COL12A1 | 6.5 | 0.020 |
| Collagen type XVI, α1 | COL16A1 | 7.2 | 0.019 |
| Collagen type VII, α1 | COL7A1 | 7.2 | 0.023 |
| Connective tissue growth factor | CTGF | 4.9 | 0.026 |
| Catenin α1 | CTNNA1 | 3.4 | 0.021 |
| Catenin β1 | CTNNB1 | 5.9 | 0.027 |
| Catenin δ1 | CTNND1 | 5.2 | 0.029 |
| Integrin αV | ITGAV | 2.8 | 0.036 |
| Integrin β1 | ITGB1 | 9.3 | 0.011 |
| Integrin β5 | ITGB5 | 2.6 | 0.035 |
| Laminin γ1 | LAMC1 | 3.0 | 0.029 |
| Matrix metallopeptidase 15 | MMP15 | 2.0 | 0.039 |
| Neural cell adhesion molecule 1 | NCAM1 | 4.7 | 0.034 |
a
Genes expressed in cells grown on TCP substrates served as a control for determining the fold-change and up- or downregulation of relevant genes in cells grown on membrane substrates.