Table 2.
Concomitant medications, timing information and invasive treatment details stratified by age
| Variable | Age (years) | p Value | |||
|---|---|---|---|---|---|
| <65 (n = 814) | 65–75 (n = 454) | 75–85 (n = 333) | ≥85 (n = 49) | ||
| Pain-to-diagnosis time (min) | 96 (52–198) | 111 (60–213) | 132 (68–240) | 97 (47–303) | <0.0001 |
| Diagnosis-to-balloon time (min) | 100 (77–138) | 109 (83–155) | 109 (80–145) | 110 (67–154) | 0.010 |
| Admission to cathlab-to-balloon time (min) | 30 (20–41) | 31 (21–45) | 32 (23–44) | 33 (20–47) | 0.11 |
| Pain-to-balloon time (min) | 216 (150–329) | 240 (165–377) | 251 (168–379) | 200 (155–425) | <0.0001 |
| Clopidogrel pre-cathlab | 33.7 | 32.8 | 28.8 | 22.4 | 0.19 |
| Clopidogrel in the cathlab | 46.7 | 46.9 | 48.3 | 36.7 | 0.38 |
| Unfractionated heparin pre-cathlab | 68.2 | 67.2 | 69.4 | 69.4 | 0.93 |
| Unfractionated heparin in the cathlab | 61.3 | 63.7 | 61.9 | 51 | 0.37 |
| Abciximab pre-cathlab | 43.5 | 46.9 | 42.9 | 34.7 | 0.12 |
| Abciximab in the cathlab | 23.5 | 21.2 | 17.7 | 26.5 | |
| No abciximab | 33 | 31.9 | 39.4 | 38.8 | |
| Femoral access | 86.4 | 84.4 | 88.3 | 87.8 | 0.45 |
| IRA in baseline angiography | |||||
| LMCA | 1.2 | 0.2 | 0.6 | 2 | 0.15 |
| LAD | 42.1 | 45.2 | 48 | 46.9 | 0.30 |
| LCX | 13.3 | 11.9 | 11.1 | 10.2 | 0.71 |
| RCA | 42.4 | 40.1 | 38.1 | 40.8 | 0.59 |
| Multi-vessel disease | 42.5 | 55.1 | 64.3 | 75.5 | <0.0001 |
| Abandoned PCI | 5.7 | 5.5 | 10.2 | 16.3 | 0.002 |
| Immediate PCI | 94.3 | 94.5 | 89.8 | 83.7 | |
| Number of patients undergoing immediate PCI (n) | 768 | 429 | 299 | 41 | |
| Stent | 94.8 | 93.5 | 88.6 | 82.9 | 0.001 |
| Drug-eluting stent | 27.9 | 24.5 | 19.7 | 9.8 | 0.005 |
| >1 stent in IRA | 21 | 20.4 | 23.4 | 26.5 | 0.85 |
| Thrombectomy | 12.2 | 11.7 | 10.4 | 12.2 | 0.86 |
| Non-IRA PCI | 4 | 5.4 | 5.7 | 4.9 | 0.55 |
| PCI complications (no-reflow, distal embolization, side branch occlusion, artery perforation) | 7.3 | 9.3 | 14.4 | 14.6 | 0.003 |
| Intra-aortic balloon pumping | 3.4 | 4.7 | 4.3 | 2.4 | 0.69 |
Values are presented as percentages or medians (inter-quartile range)
IRA infarct-related artery, LAD left anterior descending, LCX circumflex artery, LMCA left main coronary artery, PCI percutaneous coronary intervention, RCA right coronary artery