Table 2.
ADP-induced platelet aggregation kinetic parameters (mean ± SD) of the control group and patients with metabolic syndrome at baseline and after 1 and 2 months of A. melanocarpa extract therapy
| ADP-induced platelet aggregation | Patients with metabolic syndrome | Control group | ||
|---|---|---|---|---|
| Baseline | 1 month | 2 months | ||
| A max (%T) | 27.3 ± 13.0 | 19.6 ± 10.0+++ | 26.2 ± 12.9 | 23.9 ± 15.5 |
| v 0 (%T/min) | 18.4 ± 13.3 | 11.8 ± 8.6++ | 16.0 ± 13.2 | 16.9 ± 12.8 |
| Tmax (s) | 376.4 ± 174.3 | 444.5 ± 168.4++ | 379.1 ± 172.7 | 347.1 ± 165.3 |
| PSCmax (%T) | 4.2 ± 2.4 | 4.4 ± 1.5 | 3.6 ± 2.7 | 4.2 ± 1.7 |
| PLT (×109/L) | 283.2 ± 72.7 | 277.3 ± 63.7 | 277.1 ± 58.0 | 244.8 ± 63.8 |
A max maximal aggregation, v 0 initial velocity, T max time needed to reach Amax, PSC max maximal platelet shape change, PLT platelet count
+++ p < 0.001; ++ p < 0.05 versus baseline