Table 2.
Relationship between Ecd expression and various clinicopathological parameters
| Parameter | Ecd expression | Significance | ||
|---|---|---|---|---|
| Low Ecd | High Ecd | Total | P value | |
| No. (%) | No. (%) | No. (%) | ||
| Patients age | ||||
| ≤50 years | 88 (41.1) | 265 (35.8) | 353 (37) | 0.156 |
| >50 years | 126 (58.9) | 475 (64.2) | 601 (63) | |
| Total | 214 | 740 | 954 | |
| Tumor size | ||||
| ≤1.5 cm | 72 (33.6) | 212 (28.8) | 284 (30) | 0.181 |
| >1.5 cm | 142 (66.4) | 522 (71.1) | 664 (70) | |
| Total | 214 | 734 | 948 | |
| Lymph node stage | ||||
| 1 | 132 (61.7) | 423 (57.6) | 555 (58.5) | 0.395 |
| 2 | 67 (31.3) | 240 (32.7) | 307 (32.4) | |
| 3 | 15 (7) | 71 (9.7) | 86 (9.1) | |
| Total | 214 | 734 | 984 | |
| Grade | ||||
| 1 | 41 (19.2) | 102 (13.9) | 143 (15.1) | 0.013 |
| 2 | 74 (34.6) | 211 (28.7) | 285 (30.1) | |
| 3 | 99 (46.3) | 421 (57.4) | 520 (54.9) | |
| Total | 214 | 734 | 984 | |
| Tubules | ||||
| 1 | 14 (6.7) | 33 (4.6) | 47 (5.1) | 0.273 |
| 2 | 70 (33.7) | 218 (30.5) | 288 (31.2) | |
| 3 | 124 (59.6) | 463 (64.8) | 587 (63.7) | |
| Total | 208 | 714 | 922 | |
| Pleomorphism | ||||
| 1 | 5 (2.4) | 6 (0.8) | 11 (1.2) | 0.151 |
| 2 | 73 (35.3) | 237 (33.3) | 310 (33.8) | |
| 3 | 129 (62.3) | 468(65.8) | 597(65) | |
| Total | 207 | 711 | 918 | |
| Mitosis | ||||
| 1 | 76 (36.5) | 216 (30.3) | 292 (31.7) | 0.032 |
| 2 | 46 (22.1) | 29 (18.1) | 175 (19) | |
| 3 | 86 (41.3) | 369 (51.7) | 455 (49.3) | |
| Total | 208 | 714 | 922 | |
| Nottingham prognostic index | ||||
| Good (3.4) | 69 (32.2) | 185 (25.3) | 254 (26.8) | 0.014 |
| Moderate (3.41–5.4) | 117 (54.7) | 393 (53.7) | 510 (53.9) | |
| Poor(4.41–5) | 28 (13.1) | 154 (21) | 182 (19.2) | |
| Total | 214 | 732 | 946 | |
| Vascular invasion | ||||
| Definite | 61 (29) | 253 (34.4) | 314 (33.2) | 0.145 |
| Negative | 149 (71) | 482 (65.6) | 631 (66.7) | |
| Total | 210 | 735 | 945 | |