TABLE 1.
Demographic data, heart rate, and blood pressure at baseline in all participants and grouped by ALOX5 genotype (“dd,” “d5,” and “55”)1
| Variable | All | “dd” | “d5” | “55” | P value2 |
| n | 116 | 33 | 53 | 30 | |
| Sex, female, % (n) | 69.8 (81) | 78.8 (26) | 71.7 (38) | 60.0 (18) | 0.27 |
| Age,3 y | 34; 25, 46 | 33; 26, 36 | 35; 24, 48 | 32; 26, 49 | 0.59 |
| BMI, kg/m2 | 27.6 ± 4.3 | 27.3 ± 4.6 | 28.3 ± 4.5 | 26.8 ± 3.6 | 0.25 |
| Body weight, kg | 78.7 ± 13.5 | 76.9 ± 14.8 | 80.1 ± 13.2 | 78.1 ± 12.5 | 0.54 |
| Compliance,34 % of capsules | 94; 81, 100 | 91; 85, 100 | 94; 77, 100 | 94; 88, 100 | 0.82 |
| Systolic blood pressure,3 mm Hg | 113 ± 13 | 110 ± 14 (112 ± 1.9)* | 115 ± 13 (114 ± 1.5) | 113 ± 14 (112 ± 2.0) | 0.15 (0.44) |
| Diastolic blood pressure,3 mm Hg | 70.4 ± 9.2 | 69.5 ± 9.8 (70.6 ± 1.4) | 71.6 ± 8.6 (70.9 ± 1.1) | 69.0 ± 9.5 (69.0 ± 1.5) | 0.27 (0.41) |
| Heart rate, bpm | 68.3 ± 9.2 | 70.5 ± 10.8 (69.9 ± 1.5) | 68.1 ± 7.9 (68.6 ± 1.2) | 66.4 ± 9.1 (66.8 ± 1.6) | 0.19 (0.41) |
Values are mean ± SD unless otherwise indicated. *Values in parentheses are mean ± SEM adjusted for sex, age, and BMI, and P values for ANOVA adjusting for these covariates.
P value for comparison among genotypes by chi-square test or ANOVA. Continuous variables that were not normally distributed were transformed to ranks for analysis.
Indicates continuous variables that were not normally distributed. Median; 25th, 75th percentiles are shown except in the case of blood pressure, where mean ± SD are shown to allow comparisons to adjusted means.
Data were available for 92 participants: 23, 42, and 25, respectively, for the “dd,” “d5,” and “55” genotypes.