TABLE 3.
Urinary iso- and neuroprostanes in Ldlr−/− mice fed the NP, HFHC-OO, or HFHC-MO diets for 12 wk1
NP | HFHC-OO | HFHC-MO | |
ng/mg creatinine | |||
F2-isoprostane | 2.2 ± 0.1a | 2.6 ± 1.1a | 4.7 ± 1.2b |
F3-isoprostane | 2.1 ± 0.1 a | 0.9 ± 0.6a | 12.5 ± 8.2b |
F4-neuroprostane | 70.7 ± 5.7a | 45.5 ± 12.8a | 110.3 ± 57.6b |
Values are means ± SD of 4 pooled samples/diet group; samples were derived from 2 separate studies. Labeled means in a row with superscripts without a common letter differ, < 0.05. HFHC-MO, high-fat–high-cholesterol with olive oil supplemented with menhadin oil; HFHC-OO, high-fat–high-cholesterol with olive oil; NP, nonpurified.