Table 3.
The effects of the NuFit active blend and Placebo on oxidative and inflammatory stress biomarkers. Twenty overweight or obese subjects received the NuFit active blend or placebo for 4 weeks. At the end of the intervention, plasma oxidative and inflammatory stress biomarkers were evaluated. Values are expressed as mean ± SE. * Denotes significant treatment effect at the indicated p-value; there were no significant differences in baseline (day 0) values between placebo and active treatment.
| Placebo | NuFit Active Blend | p-value | ||||
|---|---|---|---|---|---|---|
| Day 0 | Day 28 | Day 0 | Day 28 | |||
| Oxidative stress biomarkers | MDA (nmol/L) | 4.2 ± 0.4 | 4.0 ± 0.2 | 4.1 ± 0.2 | 3.2 ± 0.3 * | <0.01 |
| 8-isoprostane F-2α (pg/mL) | 42.0 ± 2.5 | 44.1 ± 3 | 43.7 ± 3.2 | 36.6 ± 3 * | <0.005 | |
| Inflammatory stress biomarkers | TNF-α (pg/mL) | 411 ± 40 | 393 ± 29 | 408 ± 22 | 334 ± 38 * | <0.01 |
| CRP (µg/mL) | 32.1 ± 9.0 | 36.8 ± 7.4 | 34.2 ± 7.4 | 22.8 ± 8.3 * | <0.01 | |
| Adiponectin (ng/mL) | 8.1 ± 1.9 | 9.6 ± 1.4 | 8.9 ± 2.7 | 15.6 ± 2.3 * | <0.001 | |