Skip to main content
. Author manuscript; available in PMC: 2012 Jul 16.
Published in final edited form as: Prostaglandins Leukot Essent Fatty Acids. 2011 May 31;85(2):75–81. doi: 10.1016/j.plefa.2011.04.024

Fig. 2.

Fig. 2

Opposing effects of PGs and LTs on mouse survival and mycobacterial clearance. (A) Survival of mice after i.t. PBS injection and daily p.o. administration of water, after i.t. infection with M. tuberculosis (Mtb) and daily p.o. administration of water, celecoxib (5 mg/kg/0.5 ml) and/or MK 886 (5 mg/kg/0.5 ml). Mice were monitored for 60 days (n = 7 mice per group). (B) Bacterial load in lungs. Tissue samples were harvested at 30 and 60 days following Mtb-infection with daily administration of water, celecoxib and/ or MK 886. Data are expressed as mean ± SEM from two independent experiments (n = 9 mice per group). * Mtb + H2O vs Mtb + celecoxib and/or MK. P < 0.05.