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. Author manuscript; available in PMC: 2013 Jul 15.
Published in final edited form as: Bioorg Med Chem. 2012 Jun 6;20(14):4217–4225. doi: 10.1016/j.bmc.2012.05.068

Figure 2.

Figure 2

Growth rate of primary B16-F10 mouse melanoma tumor cells in athymic mice (A) and inhibition of tumor angiogenesis (B) and metastasis (C) in response to 21 and 7 given at 35 mg/kg 3 × weekly (M, W, F)

*** = P<0.001, **P<0.05 by one-way ANOVA and Neuman-Keuls post-test. N= 7–10. Average metastasis in untreated group- 2.5/lobe.