Table I.
Histology of pNTs with Genotype-Phenotype Discordance (n=51)
| Bull’s Eye Tumors
|
Conventional Tumors
|
||||||
|---|---|---|---|---|---|---|---|
| Category - Subtype - MKI | Age at Dx (months) | Prominent Nucleoli (%) | N-myc Protein | Category - Subtype - MKI | Age at Dx (months) | Prominent Nucleoli (%) | N-myc Protein |
| NB-PD-L | 12 | 90 | NB-PD-L | 1 | 5 | ||
| NB-PD-I | 13 | 80 | positive | NB-PD-L | 1 | 5 | negative |
| NB-PD-I | 17 | 70 | NB-PD-L | 2 | 5 | ||
| NB-PD-I | 10 | 50 | NB-PD-L | 3 | 5 | ||
| NB-PD-L | 12 | 50 | positive | NB-PD-L | 7 | 5 | |
| NB-PD-I | 10 | 40 | positive | NB-PD-I | 9 | 5 | |
| NB-PD-L | 13 | 40 | positive | NB-PD-I | 9 | 5 | |
| NB-PD-L | 3 | 30 | positive | NB-PD-I | 13 | 5 | |
| NB-PD-L | 11 | 25 | NB-PD-L | 15 | 5 | ||
| NB-PD-L | 13 | 25 | positive | NB-PD-L | 5 days | 0 | |
| NB-PD-I | 16 | 25 | NB-PD-I | 5 days | 0 | ||
| NB-PD-I | 5 | 20 | positive | NB-PD-L | 18 days | 0 | |
| NB-PD-I | 4 | 15 | negative | NB-PD-L | 1 | 0 | |
| NB-PD-I | 12 | 15 | positive | NB-PD-L | 2 | 0 | |
| NB-PD-L | 4 | 10 | positive | NB-PD-I | 3 | 0 | |
| NB-PD-L | 15 | 10 | positive | NB-PD-L | 5 | 0 | |
| NB-PD-L | 5 | 0 | |||||
| NB-PD-L | 5 | 0 | negative | ||||
| NB-PD-I | 6 | 0 | |||||
| NB-PD-L | 6 | 0 | |||||
| NB-PD-I | 6 | 0 | negative | ||||
| NB-PD-I | 7 | 0 | negative | ||||
| NB-PD-I | 8 | 0 | |||||
| NB-PD-L | 9 | 0 | negative | ||||
| NB-PD-I | 15 | 0 | |||||
| NB-PD-L | 17 | 0 | negative | ||||
| NB-D-L | 17 | 0 | negative | ||||
| NB-D-L | 17 | 0 | negative | ||||
| NB-D-L | 19 | 0 | |||||
| NB-D-L | 22 | 0 | negative | ||||
| GNB-I | 57 | 0 | |||||
| GNB-I | 70 | 0 | |||||
| GNB-I | 73 | 0 | negative | ||||
| GN-mtrng | 39 | 0 | |||||
| GN-mtrng | 74 | 0 | negative | ||||
pNTs, peripheral neuroblastic tumors; Age at Dx, age at diagnosis; NB, neuroblastoma; PD, poorly differentiated; D, differentiating; GNB-I, ganglioneuroblastoma intermixed; GN-mtrng, ganglioneuroma maturing; MKI, mitosis and karyorrhexis index; L, low; I, intermediate.