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. Author manuscript; available in PMC: 2012 Jul 16.
Published in final edited form as: J Mol Cell Cardiol. 2010 Nov 11;50(1):239–247. doi: 10.1016/j.yjmcc.2010.11.002

Fig. 6. Trx1 overexpression increased the HIF-1α DNA binding activity after MI.

Fig. 6

EMSA analysis revealed increased nuclear translocation and DNA binding activity of HIF-1α in TMI compared to WMI (n=3 from each group). The position of the HIF-1α band was confirmed by the disappearance of the corresponding band in the last lane from right side when we used unlabelled probe (Cold probe). WS indicates wild type sham; TS, Trx1 transgenic sham; WMI, wild type animals subjected to MI; TMI, Trx1 transgenic animals subjected to MI; NS, non-specific.