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(a) Image from the RCSB PD of PDB ID 1A8D [47]; (b) Illustration of the carbohydrate-binding sites for lactose (LAC), galactose (GAL), sialic acid (SIA) and N-acetyl-galactosamine (NGA) in tetanus toxin. These binding sites are localized in the beta-trefoil domain of fragment C (residues 865–1315). Adapted from [40].
