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Amino acid distribution in 13 amino acid long VH CDR3 observed in sequenced clones at VH CDR3 loop. Distribution of amino acids at each position of the 13-amino acid long VH CDR3 from sequenced clones in the in vivo selected library (PS: post-selection) and predicted from the oligonucleotide sequences (T); see also additional file 2 in [22]. White arrows indicate over-represented amino acid after in vivo selection.
