FIGURE 6.

Comparison of the time courses of contraction of intact rat caudal arterial smooth muscle in response to: (i) KCl in the presence of extracellular Ca²⁺, (ii) calyculin-A in the presence of extracellular Ca²⁺, and (iii) a combination of KCl and calyculin-A in the presence of extracellular Ca²⁺. Membrane-intact rat caudal arterial smooth muscle strips, mounted on a force transducer in Ca²⁺-containing H-T buffer, were treated with KCl (87 mm) (red trace), calyculin-A (0.5 μm) (green trace), or both KCl and calyculin-A (black trace). The arrow indicates the time of application of the contractile stimulus.