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Activities of wild-type mouse Ugt3a1 and Ugt3a2 with various aglycone substrates and either UDP-Glc or UDP-GlcNAc as sugar donor
| Protein variant | Activity with UDP-Glc |
Activity with UDP-GlcNAc |
||
|---|---|---|---|---|
| 4-MUa | UDCA | 4-MU | UDCA | |
| pmol/min/mg | pmol/min/mg | |||
| Ugt3a1 | 3.08 | 5.56 | ND | ND |
| Ugt3a2 | 4.77 | 2.84 | ND | ND |
a 4-MU, 4-methylumbelliferone; UDCA, ursodeoxycholic acid; ND, not detected.
